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Tom’s Weight LossRankings

Supplements

Best metabolic health supplements

Berberine, fibre and probiotic products sold for metabolic support, compared on ingredient disclosure and research quality.

Metabolic markers — glucose, HbA1c, lipids — are where this category has its most credible research, particularly berberine. Effects on weight specifically are much smaller. Read the ingredient guides before the product pages.

Featured placement

This position was chosen by us, not produced by our evidence ordering, and it did not earn the spot by out-performing anything. No money is involved — we are not paid for it and earn no commission on it. Everything below is ordered on published evidence as normal. Full terms

#1Featured placementThird-party tested

CoreAge Rx GLP-1 Support

A three-strain probiotic with prebiotic fibre, targeting the gut rather than appetite directly

Form
Delayed-release vegetarian capsule
From
$23.83

Ordered by disclosure, below the featured placement

#2Third-party tested

CoreAge Rx Full House

Four fibres in one capsule at $19 a month, from the same company that sells the prescription

Form
Capsule
From
$19
#4Third-party tested

Utzy Naturals Berbercol

600mg berberine with citrus bergamot, and a 90-day empty-bottle guarantee

Form
Capsule
From
Not published
#5

GOLO Release

Sold only alongside the company's own diet programme, with a money-back guarantee

Form
Vegetarian capsule
From
$34.95
#6

Lemme Lemme GLP-1

Publishes every active ingredient with a dose and a standardisation — rare here

Form
Capsule
From
$30
#7

Pendulum Akkermansia

The best-known Akkermansia product, from the company that commercialised the strain

Form
Capsule
From
$30
#9

1MD Nutrition BiomeMD

62 billion CFUs across 16 strains, with a 90-day money-back guarantee

Form
Capsule
From
$40
#10

Satiety Now Berberine HCl Capsules

Berberine alongside an inulin product, from a brand naming GLP-1 stimulation directly

Form
Capsule (berberine) and powder (inulin)
From
Not published
#15

Solaray Berberine 500mg

Publishes exactly which plants the berberine comes from, and how much from each

Form
Capsule
From
$23.99
#24

Ritual Synbiotic+

Three-in-one prebiotic, probiotic and postbiotic with delayed-release delivery

Form
Capsule
From
$43.2