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Tom’s Weight LossRankings

Supplements

Best protein supplements for muscle loss on a GLP-1

Protein and creatine products for preserving lean mass during GLP-1 weight loss, compared on published grams per serving.

A substantial share of the weight lost on a GLP-1 is lean tissue, and appetite suppression makes it easy to fall well short of protein without noticing. Protein intake and resistance training are the two interventions with real evidence for holding on to muscle; a supplement can deliver the first. Judge these on grams per serving, which is the only figure that matters — and note that a shake is an adjunct to training, not a substitute for it.

Ordered by disclosure

#1Third-party tested

CoreAge Rx Strong Suit

5g of plain creatine monohydrate, nothing else — the correct dose of the best-evidenced ingredient on this site

Form
Unflavoured powder — one 5g scoop daily
From
$19
#2Third-party tested

Momentous Berberine

NSF Certified for Sport berberine — but 550mg is the complex, not the berberine

Form
Capsule — 1 to 3 daily before meals
From
$37.49
#3Third-party tested

SoWell Protein

25g of whey isolate per serving, third-party tested, aimed at lean mass on a GLP-1

Form
Powder in single-serve packets
From
$40.49
#4Third-party tested

Ritual GLP-1 Nutrition Support

Publishes every amount with %DV, names its suppliers, and does not pretend to be a weight product

Form
Capsule multivitamin plus plant-based protein powder
From
$77
#6Third-party tested

Codeage Gut Muscle Formula

Six ingredients around the gut-muscle axis — with one CFU count published and the rest unquantified

Form
Flavoured powder — chocolate brownie
From
$54.99
#7Third-party tested

SoWell Balanced Berberine

900mg of berberine HCl with 400mcg chromium — both amounts published, both third-party tested

Form
Capsule
From
$37.8
#8

Herbalife GLP-1 Nutrition Companion

States twice that it is not a drug and does not promote GLP-1 drugs — then sells a $219.99 protein and fibre bundle

Form
Powder bundle — meal replacement shake
From
$219.99
#12

NutraChamps Digestive Enzymes

A broad-spectrum enzyme blend for the digestive complaints that come with slowed gastric emptying

Form
Capsule
From
$20
#15

Calocurb GLP-1 Activator

One of the very few products here with published human data on gut hormone release — and a headline claim that needs unpacking

Form
Capsule
From
$89.95
#16

WeightCare GLP-1 Support Bundle

Collagen, multivitamin and plant protein for people on semaglutide or tirzepatide, at $164.95

Form
Three-product bundle
From
$164.95
#17

Xyngular GLP-1 Support Stack

20 g of grass-fed whey isolate in a three-part stack — sold through a multi-level distribution model

Form
Three-product stack — protein
From
$195
#19

Novomins GLP-1 Support Bundle

Three gummies — vinegar, magnesium and fibre — with claims phrased as nutrient functions rather than outcomes

Form
Gummy
From
$60
#21

Invigor8 Collagen Peptides

Hydrolysed types I, II and III with vitamin C — sound for skin and joints, weaker for the muscle claim

Form
Powder
From
$34.95
#22

Glow GLP1 Support Stack

Protein plus two vitamin products in a starter bundle at $70.55, with nothing quantified

Form
Three-product bundle with shaker
From
$70.55