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Tom’s Weight LossRankings

Supplements

Best berberine supplements for metabolic support

Berberine products compared on published dose, botanical sourcing and standardisation — plus the drug interaction issue their marketing omits.

Berberine has the strongest ingredient-level research in this category and the most misleading nickname. It acts on AMPK, not the GLP-1 receptor. It also inhibits CYP3A4 and can raise blood levels of common prescription medications, which makes it a pharmacist conversation before it is a shopping decision.

Ordered by disclosure

#1Third-party tested

Utzy Naturals Berbercol

600mg berberine with citrus bergamot, and a 90-day empty-bottle guarantee

Form
Capsule
From
Not published
#2

Satiety Now Berberine HCl Capsules

Berberine alongside an inulin product, from a brand naming GLP-1 stimulation directly

Form
Capsule (berberine) and powder (inulin)
From
Not published
#3

Solaray Berberine 500mg

Publishes exactly which plants the berberine comes from, and how much from each

Form
Capsule
From
$23.99