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Supplements

Protein and satiety: the least marketed, best supported thing here

If you take one thing from these supplement guides, make it this one. Protein is unglamorous, well evidenced, and the thing most people getting thinner are getting wrong.

By Tom · 6 min read · updated

The satiety evidence

Protein is consistently the most satiating macronutrient. Higher-protein meals reduce subsequent intake more than equivalent-calorie meals higher in carbohydrate or fat, and this shows up reliably across studies.

That effect is larger and better replicated than anything a fibre or probiotic capsule produces.

Why it matters more on a GLP-1

Weight lost rapidly from any cause includes lean tissue, not only fat. GLP-1 medications can reduce intake sharply, which makes inadequate protein much easier to fall into.

Losing muscle alongside fat leaves you lighter but weaker, lowers resting energy expenditure, and makes regain more likely if you stop. Adequate protein and resistance training are the countermeasures.

Very few telehealth GLP-1 programmes provide meaningful support on this, which is one of the things we look for when assessing them.

Food first, powder second

Protein from food comes with micronutrients, volume and satiety a shake does not replicate. Eggs, dairy, fish, meat, legumes and soy all do the job.

A protein supplement is a convenience for closing a gap — a skipped breakfast, a day when appetite is suppressed and eating is hard. That is a legitimate use, and a different thing from a weight loss product.

What to look for in a powder

A meaningful protein dose per serving rather than a token amount padded with carbohydrate. Third-party testing, because protein powders have a documented history of heavy metal contamination. And a short ingredient list you can read.

Products marketed on weight loss rather than on protein content deserve more scepticism, not less.

If appetite suppression is making eating hard

This is common on GLP-1 medication and worth raising with your prescriber rather than working around alone. Persistently very low intake is not the goal of treatment and causes its own problems.

A protein shake can be a practical bridge on difficult days. It is not a substitute for a conversation about whether your dose is right.

Sources

Clinical and regulatory guidance changes. Check the current version of any source before relying on it.

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